Implementation of the Chick Chorioallantoic Membrane (CAM) Model in Radiation Biology and Experimental Radiation Oncology Research.

Radiotherapy (RT) is a component of commonplace most cancers therapy. Innovations in therapy planning and elevated precision in dose supply have considerably improved the therapeutic achieve of radiotherapy however are reaching their limits attributable to biologic constraints. Thus, a greater understanding of the complicated native and systemic responses to RT and of the organic mechanisms inflicting therapy success or failure is required if we intention to outline novel targets for organic remedy optimization. Moreover, optimum therapy schedules and prognostic biomarkers should be outlined for assigning sufferers to the finest therapy choice. The complexity of the tumor setting and of the radiation response requires intensive in vivo experiments for the validation of such remedies. So far in vivo investigations have largely been carried out in time- and cost-intensive murine fashions.

Here we suggest the implementation of the chick chorioallantoic membrane (CAM) mannequin as a quick, cost-efficient mannequin for semi high-throughput preclinical in vivo screening of the modulation of the radiation results by molecularly focused medication. This evaluate offers a complete overview on the utility spectrum, benefits and limitations of the CAM assay and summarizes present data of its applicability for most cancers analysis with particular concentrate on analysis in radiation biology and experimental radiation oncology. As scholar populations turn out to be extra numerous, it’s important for educators, directors, and establishments to implement practices that guarantee the success of all college students.

This is especially true in the sciences, as college students from historically underrepresented populations in STEM compose an more and more better proportion of the nationwide scholar demographic. The Teaching Section of the American Physiological Society sponsored a symposium, “Inclusive Practices for Diverse Student Populations,” at 2017 Experimental Biology in Chicago, IL, introducing practices that promote inclusion in numerous scholar populations in STEM. The symposium started with an introduction to quantitative and qualitative evaluation methods of fairness and inclusion. The second half of the symposium mentioned structural bias and efficient inclusive practices.

Using Experimental Data and Information Criteria to Guide Model Selection for Reaction-Diffusion Problems in Mathematical Biology.

Reaction-diffusion fashions describing the motion, copy and demise of people inside a inhabitants are key mathematical modelling instruments with widespread purposes in mathematical biology. A various vary of such continuum fashions have been utilized in varied organic contexts by selecting completely different flux and supply phrases in the reaction-diffusion framework.

For instance, to explain the collective spreading of cell populations, the flux time period could also be chosen to mirror varied motion mechanisms, comparable to random movement (diffusion), adhesion, haptotaxis, chemokinesis and chemotaxis. The alternative of flux phrases in particular purposes, comparable to wound therapeutic, is often made heuristically, and hardly ever it’s examined quantitatively in opposition to detailed cell density information. More usually, in mathematical biology, the questions of mannequin validation and mannequin choice haven’t acquired the identical consideration as the questions of mannequin growth and mannequin evaluation. Many research don’t think about mannequin validation or mannequin choice, and those who do usually base the choice of the mannequin on residual error standards after mannequin calibration is carried out utilizing nonlinear regression methods.

In this work, we current a mannequin choice case research, in the context of cell invasion, with a really detailed experimental information set. Using Bayesian evaluation and info standards, we reveal that mannequin choice and mannequin validation ought to account for each residual errors and mannequin complexity. These issues are sometimes missed in the mathematical biology literature. The outcomes we current right here present an easy methodology that can be utilized to information mannequin choice throughout a variety of purposes. Furthermore, the case research we current offers a transparent instance the place neglecting the function of mannequin complexity may give rise to deceptive outcomes.

Implementation of the Chick Chorioallantoic Membrane (CAM) Model in Radiation Biology and Experimental Radiation Oncology Research.
Implementation of the Chick Chorioallantoic Membrane (CAM) Model in Radiation Biology and Experimental Radiation Oncology Research.

Identification of mineralocorticoid and glucocorticoid receptors on peripheral nociceptors: Translation of experimental findings from animal to human biology.

Evidence is accumulating that activation of mineralocorticoid (MR) and glucocorticoid (GR) receptors on peripheral sensory neurons modulates ache sensation. While the expression and actual anatomical localization of MR and GR in the varied subpopulations of peripheral sensory neurons has been proven in animals, it’s nonetheless unknown for the human pores and skin.

Therefore, we aimed to establish MR and GR mRNA and protein in addition to the actual subpopulations of sensory neurons in human versus rat pores and skin. Tissue samples from rat and human pores and skin have been subjected to RT-PCR, Western blot and double immunofluorescence confocal evaluation of MR and GR with the neuronal markers calcitonin gene-related peptide (CGRP), neurofilament 200 (NF200) and tyrosine hydroxylase (TH). Using RT-PCR we have been in a position to isolate MR in addition to GR particular transcripts from human pores and skin. Consistently, Western blot evaluation recognized MR- in addition to GR- particular protein bands at the anticipated molecular weights of 110 and 87 kD, respectively.

Guanidine - Hydrochloride (Molecular Biology Grade)

CE162 500 g
EUR 194

Guanidine - Hydrochloride (Molecular Biology Grade)

CE163 1 kg
EUR 294

Guanidine Thiocyanate (Molecular Biology Grade)

CE164 100 g
EUR 72

Guanidine Thiocyanate (Molecular Biology Grade)

CE165 500 g
EUR 160

Guanidine Thiocyanate (Molecular Biology Grade)

CE166 1 kg
EUR 256

Tris - Hydrochloride (Molecular Biology Grade)

CE234 250 g
EUR 83

Tris - Hydrochloride (Molecular Biology Grade)

CE235 500 g
EUR 120

Tris - Hydrochloride (Molecular Biology Grade)

CE236 1 kg
EUR 186

Guanidine (hydrochloride)

HY-B0178A 50g
EUR 133

Guanidine hydrochloride

GB0242 100g
EUR 67.4
  • Product category: Biochemicals/Biology Reagents/Protein Related

Urea, suitable for molecular biology

GE1210-1KG 1 kg
EUR 89

Urea, suitable for molecular biology

GE1210-500G 500 g
EUR 64

Guanidine hydrochloride, 99%

GE1914-100G 100 g
EUR 46

Guanidine hydrochloride, 99%

GE1914-1KG 1 kg
EUR 110

Guanidine hydrochloride, 99%

GE1914-250G 250 g
EUR 54

Guanidine hydrochloride, 99%

GE1914-25G 25 g
EUR 42

Guanidine hydrochloride, 99%

GE1914-500G 500 g
EUR 74

Sucrose, GlenBiol, suitable for molecular biology

GC3201-1KG 1 kg
EUR 75

BCIP (Molecular Biology Grade)

CE108 250 mg
EUR 63

BCIP (Molecular Biology Grade)

CE109 1 g
EUR 90

CHAPS (Molecular Biology Grade)

CE114 1 g
EUR 55

CHAPS (Molecular Biology Grade)

CE115 5 g
EUR 131

CHAPS (Molecular Biology Grade)

CE116 25 g
EUR 410

DAPI (Molecular Biology Grade)

CE117 5 mg
EUR 60

DAPI (Molecular Biology Grade)

CE118 25 mg
EUR 133

DAPI (Molecular Biology Grade)

CE119 100 mg
EUR 319

Dimethylsulfoxide (Molecular Biology Grade)

CE120 100 ml
EUR 55

Dimethylsulfoxide (Molecular Biology Grade)

CE121 500 ml
EUR 92

DTT (Molecular Biology Grade)

CE131 5 g
EUR 78

DTT (Molecular Biology Grade)

CE132 10 g
EUR 111

DTT (Molecular Biology Grade)

CE133 25 g
EUR 203

Glycine (Molecular Biology Grade)

CE158 1 kg
EUR 70

Glycine (Molecular Biology Grade)

CE159 5 kg
EUR 190

HEPES (Molecular Biology Grade)

CE171 100 g
EUR 82

HEPES (Molecular Biology Grade)

CE172 500 g
EUR 224

HEPES (Molecular Biology Grade)

CE173 1 kg
EUR 354

Lysozyme (Molecular Biology Grade)

CE188 1 g
EUR 59

Lysozyme (Molecular Biology Grade)

CE189 10 g
EUR 206

NAD (Molecular Biology Grade)

CE196 1 g
EUR 60

NAD (Molecular Biology Grade)

CE197 5 g
EUR 138

NBT (Molecular Biology Grade)

CE209 1 g
EUR 103

NBT (Molecular Biology Grade)

CE210 5 g
EUR 300

Tris (Molecular Biology Grade)

CE237 500 g
EUR 89

Tris (Molecular Biology Grade)

CE238 1 kg
EUR 128

Tris (Molecular Biology Grade)

CE239 5 kg
EUR 446

Tween20 (Molecular Biology Grade)

CE242 1 l
EUR 89

Water (Molecular Biology Grade)

CE243 500 ml
EUR 52

Water (Molecular Biology Grade)

CE244 1 l
EUR 56

Ammonium sulfate (Molecular Biology Grade)

CE105 250 g
EUR 46

Ammonium sulfate (Molecular Biology Grade)

CE106 1 kg
EUR 60

Ammonium sulfate (Molecular Biology Grade)

CE107 5 kg
EUR 128

Bis-Acrylamid (Molecular Biology Grade)

CE110 50 g
EUR 79

Bis-Acrylamid (Molecular Biology Grade)

CE111 250 g
EUR 216

Formamide deionized (Molecular Biology Grade)

CE145 500 ml
EUR 73

Formamide deionized (Molecular Biology Grade)

CE146 1 l
EUR 100

Glycerol 87 % (Molecular Biology Grade)

CE154 1 l
EUR 78

Glycerol waterfree (Molecular Biology Grade)

CE155 500 ml
EUR 65

Glycerol waterfree (Molecular Biology Grade)

CE156 1 l
EUR 85

Glycerol waterfree (Molecular Biology Grade)

CE157 2.5 l
EUR 142

Urea Crystalline (Molecular Biology Grade)

CE167 1 kg
EUR 60

Urea Crystalline (Molecular Biology Grade)

CE168 5 kg
EUR 151

MOPS buffer (Molecular Biology Grade)

CE194 100 g
EUR 85

MOPS buffer (Molecular Biology Grade)

CE195 250 g
EUR 141

Sodium chloride (Molecular Biology Grade)

CE205 500 g
EUR 52

Sodium chloride (Molecular Biology Grade)

CE206 1 kg
EUR 59

Sodium chloride (Molecular Biology Grade)

CE207 5 kg
EUR 103

D(+)-Sucrose (Molecular Biology Grade)

CE224 500 g
EUR 56

D(+)-Sucrose (Molecular Biology Grade)

CE225 1 kg
EUR 70

D(+)-Sucrose (Molecular Biology Grade)

CE226 5 kg
EUR 173

TritonX-100 (Molecular Biology Grade)

CE240 500 ml
EUR 56

TritonX-100 (Molecular Biology Grade)

CE241 1 l
EUR 66

Water, Ultrapure Molecular Biology Grade

41024-4L 4L
EUR 121
Description: Minimum order quantity: 1 unit of 4L

Tween 20, Molecular Biology Grade

T9100-010 100ml
EUR 72

Tween 20, Molecular Biology Grade

T9100-050 500ml
EUR 111

Tween 20, Molecular Biology Grade

T9100-100 1L
EUR 134

Water, distilled, GlenBiol™, suitable for molecular biology

GK8512-1L 1 l
EUR 77

Agarose, low EEO, GlenBiol, suitable for molecular biology

GE6258-100G 100 g
EUR 181

Phenol, (Carbolic acid) Double distilled for Molecular Biology

PD0252 500g
EUR 160.49
  • Product category: Biochemicals/Misc. Biochemicals

Guanidine hydrochloride (6 M) solution

B1013-1L
EUR 251

Guanidine hydrochloride (6 M) solution

B1013-4L
EUR 588

EDTA - Dinatriumsalz - Dihydrat (Molecular Biology Grade)

CE135 250 g
EUR 60

EDTA - Dinatriumsalz - Dihydrat (Molecular Biology Grade)

CE136 500 g
EUR 72

EDTA - Dinatriumsalz - Dihydrat (Molecular Biology Grade)

CE137 1 kg
EUR 104

EDTA - Dinatriumsalz - Dihydrat (Molecular Biology Grade)

CE138 5 kg
EUR 349

D(+)-Glucose waterfree (Molecular Biology Grade)

CE148 500 g
EUR 56

D(+)-Glucose waterfree (Molecular Biology Grade)

CE149 1 kg
EUR 63

D(+)-Glucose waterfree (Molecular Biology Grade)

CE150 5 kg
EUR 150

Yeast extract powder (Molecular Biology Grade)

CE169 500 g
EUR 111

Hyaluronidase Grade I (Molecular Biology Grade)

CE174 1 g
EUR 194

Hyaluronidase Grade I (Molecular Biology Grade)

CE175 5 g
EUR 767

Magnesium acetate - Tetrahydrate (Molecular Biology Grade)

CE190 500 g
EUR 82

NADH - Disodium salt (Molecular Biology Grade)

CE198 1 g
EUR 76

NADH - Disodium salt (Molecular Biology Grade)

CE199 5 g
EUR 204

NADP - sodium salt (Molecular Biology Grade)

CE200 250 mg
EUR 77

NADP - sodium salt (Molecular Biology Grade)

CE201 1 g
EUR 159

NADPH - Tetrasodium salt (Molecular Biology Grade)

CE202 25 mg
EUR 59

NADPH - Tetrasodium salt (Molecular Biology Grade)

CE204 500 mg
EUR 312

SSC Buffer (20X) (Molecular Biology Grade)

CE229 1 l
EUR 72

XTT sodium salt (Molecular Biology Grade)

CE250 100 mg
EUR 174

XTT sodium salt (Molecular Biology Grade)

CE251 500 mg
EUR 510

Albumin fraction V (pH7,0) (Molecular Biology Grade)

CE100 50 g
EUR 107

Albumin fraction V (pH7,0) (Molecular Biology Grade)

CE101 100 g
EUR 161

Albumin fraction V (pH7,0) (Molecular Biology Grade)

CE102 250 g
EUR 323

Albumin fraction V (pH7,0) (Molecular Biology Grade)

CE103 500 g
EUR 547

Albumin fraction V (pH7,0) (Molecular Biology Grade)

CE104 1 kg
EUR 969

EDTA solution pH 8.0 (0.5 M) (Molecular Biology Grade)

CE141 500 ml
EUR 73

LB-Agar - Powder according to Lennox (Molecular Biology Grade)

CE178 500 g
EUR 91

LB-Agar - Powder according to Lennox (Molecular Biology Grade)

CE179 2.5 kg
EUR 251

LB-Agar - Powder according to Miller (Molecular Biology Grade)

CE180 500 g
EUR 87

LB-Agar - Powder according to Miller (Molecular Biology Grade)

CE181 2.5 kg
EUR 246

LB-Medium - Powder according to Lennox (Molecular Biology Grade)

CE182 500 g
EUR 90

LB-Medium - Powder according to Lennox (Molecular Biology Grade)

CE183 2.5 kg
EUR 251

LB-Medium - Powder according to Miller (Molecular Biology Grade)

CE184 2.5 kg
EUR 246

Agarose LE, Ultra-Pure Molecular Biology Grade, 100 g

41028-100G 100G
EUR 222
Description: Minimum order quantity: 1 unit of 100G

Agarose LE, Ultra-Pure Molecular Biology Grade, 25 g

41028-25G 25G
EUR 109
Description: Minimum order quantity: 1 unit of 25G

Agarose LE, Ultra-Pure Molecular Biology Grade, 500 g

41028-500G 500G
EUR 719
Description: Minimum order quantity: 1 unit of 500G

Guanidine HCl

B1949-5.1 10 mM (in 1mL DMSO)
EUR 108
Description: Guanidine HCl, the crystalline compound of strong alkalinity formed by the oxidation of guanine, is a normal product of protein metabolism and a protein denaturant.

Guanidine HCl

B1949-50 50 mg
EUR 128
Description: Guanidine HCl, the crystalline compound of strong alkalinity formed by the oxidation of guanine, is a normal product of protein metabolism and a protein denaturant.

Guanidine thiocyanate

GE1694-100G 100 g
EUR 49

Guanidine thiocyanate

GE1694-1KG 1 kg
EUR 110

Guanidine thiocyanate

GE1694-250G 250 g
EUR 61

Guanidine thiocyanate

GE1694-500G 500 g
EUR 78

Guanidine thiocyanate

GE1694-5KG 5 kg
EUR 285

Guanidine Thiocyanate

20-abx082115
  • EUR 217.00
  • EUR 175.00
  • 100 g
  • 25 g
  • Shipped within 5-10 working days.

Guanidine Thiocyanate

20-abx082390
  • EUR 217.00
  • EUR 175.00
  • 100 g
  • 25 g
  • Shipped within 5-10 working days.

Guanidine Hcl

abx082517-500g 500 g
EUR 189
  • Shipped within 5-10 working days.

Guanidine thiocyanate

GB0244 250g
EUR 84.8
  • Product category: Biochemicals/Biology Reagents/DNA/RNA Purification

Guanidine thiocyanate

GDR0244 250g
EUR 79.58
  • Product category: Biochemicals/Biology Reagents/DNA/RNA Purification

AGAROSE LE, LOW EEO, MOLECULAR BIOLOGY GRADE, 100G PER UNIT

AGR-LE-100 1/pk
EUR 168
Description: Bioscience Mol Bio; Agarose

Guanidine thiocyanate Ultrapure

G019-10x25G 10 x 25 g
EUR 151

Guanidine thiocyanate Ultrapure

G019-4x25G 4 x 25 g
EUR 70

Guanidine HCl, 2kg

R5001-2kg
EUR 401

Guanidine HCl, 500g

R5001-500g
EUR 190

Guanidine Thiocyanate, 500g

R5938-500g
EUR 197

Guanidine Hcl, Low ASH

abx082516-500g 500 g
EUR 189
  • Shipped within 5-10 working days.

AGAROSE LE, LOW EEO, MOLECULAR BIOLOGY GRADE, 500G/UNIT, 10 UNITS PER CASE

AGR-LE-5001 1/pk
EUR 3058
Description: Bioscience Mol Bio; Agarose

AGAROSE MS, PCR SCREENING, MOLECULAR BIOLOGY GRADE, 100G/UNIT, 10 UNITS PER CASE

AGR-MS-1001 1/pk
EUR 2038
Description: Bioscience Mol Bio; Agarose

100 ML, MOLECULAR BIOLOGY GRADE WATER; TESTED TO USP STERILE PURIFIED WATER SPECIFICATIONS

46-000-CI 100 mL/pk
EUR 57
Description: Media Catalog; Sterile Wi-Fi Qual, Cell

1 L, MOLECULAR BIOLOGY GRADE WATER; TESTED TO USP STERILE PURIFIED WATER SPECIFICATIONS

46-000-CM 1L/pk
EUR 98
Description: Media Catalog; Sterile Wi-Fi Qual, Cell

500 ML, MOLECULAR BIOLOGY GRADE WATER; TESTED TO USP STERILE PURIFIED WATER SPECIFICATIONS

46-000-CV 500 mL/pk
EUR 106
Description: Media Catalog; Sterile Wi-Fi Qual, Cell

AGAROSE LE, LOW EEO, MOLECULAR BIOLOGY GRADE, 100G PER UNIT, 10 UNITS PER CASE

AGR-LE-1001 1/pk
EUR 772
Description: Bioscience Mol Bio; Agarose

AGAROSE LM, LOW MELTING, MOLECULAR BIOLOGY GRADE, 100G/UNIT, 10 UNITS PER CASE (AL)

AGR-LM-1001 1/pk
EUR 3737
Description: Bioscience Mol Bio; Agarose

AGAROSE LM, LOW MELTING, MOLECULAR BIOLOGY GRADE, 50G/UNIT, 10 UNITS PER CASE (AL)

AGR-LM-501 1/pk
EUR 2075
Description: Bioscience Mol Bio; Agarose

30UL CLEAR PIPET TIPS FOR MOLECULAR DEVICE LIBERTY.

LT-384-R 3840/pk
EUR 2193
Description: Robotic Tips; Robotic tips - Axygen

Agarose, Molecular Grade

BIO-41025 500g Ask for price

Agarose, Molecular Grade

BIO-41026 100g Ask for price

Molecular Weight Marker

abx098957-15ul 15 ul
EUR 105
  • Shipped within 1-2 working days.

ELISA kit for Human LMWK (Low Molecular Weight Kininogen)

ELK1799 1 plate of 96 wells
EUR 432
  • The microtiter plate provided in this kit has been pre-coated with an antibody specific to Low Molecular Weight Kininogen (LMWK). Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody specific
  • Show more
Description: A sandwich ELISA kit for detection of Low Molecular Weight Kininogen from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

ELISA kit for Human HMWK (High Molecular Weight Kininogen)

ELK2201 1 plate of 96 wells
EUR 432
  • The microtiter plate provided in this kit has been pre-coated with an antibody specific to High Molecular Weight Kininogen (HMWK). Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody specifi
  • Show more
Description: A sandwich ELISA kit for detection of High Molecular Weight Kininogen from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

ELISA kit for Mouse HMWK (High Molecular Weight Kininogen)

ELK7788 1 plate of 96 wells
EUR 432
  • The microtiter plate provided in this kit has been pre-coated with an antibody specific to High Molecular Weight Kininogen (HMWK). Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody specifi
  • Show more
Description: A sandwich ELISA kit for detection of High Molecular Weight Kininogen from Mouse in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

DiscoveryProbe? Cancer Biology-related Compounds Panel

L1003-5 5 mg/well
EUR 3947
Description: A wide range of well-characterized bioactive molecules that covers various targets related to cancer biology, including p53, EGFR and PKC etc. Facilitate your research towards the insights of gene regulation, tumorgenesis and immunotherapy etc.

Holder for Plasmid Midi, Maxi and Maxi plus, Ion Exchange column

FAPDE-holder-for-ion-exchange 1 prep
EUR 158

Semicarbazide hydrochloride ELISA Kit (OKAO00100)

OKAO00100 96 Wells
EUR 753
Description: Description of target: Snow white crystals. Used as a reagent for ketones and aldehydes with which it affords crystalline compounds having characteristic melting points.;Species reactivity: General;Application: ;Assay info: Assay Methodology: Competitive Inhibition ELISA;Sensitivity:
ComponentAmount
Tissue0.1 ppb
Liver0.1 ppb
Honey, milk0.1 ppb
Intestine0.1 ppb

ELISA kit for Human ADP-HMW (High Molecular Weight Adiponectin)

E-EL-H5621 1 plate of 96 wells
EUR 534
  • Gentaur's ADP-HMW ELISA kit utilizes the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Human ADP-HMW. Standards or samples are added to the micro ELISA plate wells and combined w
  • Show more
Description: A sandwich ELISA kit for quantitative measurement of Human ADP-HMW (High Molecular Weight Adiponectin) in samples from Serum, Plasma, Cell supernatant

ELISA kit for Mouse LOW Molecular Weight Adiponectin (LOW-ADP)

KTE71573-48T 48T
EUR 354
Description: Quantitative sandwich ELISA for measuring Mouse LOW Molecular Weight Adiponectin (LOW-ADP) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Mouse LOW Molecular Weight Adiponectin (LOW-ADP)

KTE71573-5platesof96wells 5 plates of 96 wells
EUR 2252
Description: Quantitative sandwich ELISA for measuring Mouse LOW Molecular Weight Adiponectin (LOW-ADP) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Mouse LOW Molecular Weight Adiponectin (LOW-ADP)

KTE71573-96T 96T
EUR 572
Description: Quantitative sandwich ELISA for measuring Mouse LOW Molecular Weight Adiponectin (LOW-ADP) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Rat LOW Molecular Weight Adiponectin (LOW-ADP)

KTE101014-48T 48T
EUR 354
Description: Quantitative sandwich ELISA for measuring Rat LOW Molecular Weight Adiponectin (LOW-ADP) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Rat LOW Molecular Weight Adiponectin (LOW-ADP)

KTE101014-5platesof96wells 5 plates of 96 wells
EUR 2252
Description: Quantitative sandwich ELISA for measuring Rat LOW Molecular Weight Adiponectin (LOW-ADP) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Rat LOW Molecular Weight Adiponectin (LOW-ADP)

KTE101014-96T 96T
EUR 572
Description: Quantitative sandwich ELISA for measuring Rat LOW Molecular Weight Adiponectin (LOW-ADP) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human High Molecular Weight Adiponectin (HMW-ADP)

KTE62971-48T 48T
EUR 354
Description: Quantitative sandwich ELISA for measuring Human High Molecular Weight Adiponectin (HMW-ADP) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human High Molecular Weight Adiponectin (HMW-ADP)

KTE62971-5platesof96wells 5 plates of 96 wells
EUR 2252
Description: Quantitative sandwich ELISA for measuring Human High Molecular Weight Adiponectin (HMW-ADP) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human High Molecular Weight Adiponectin (HMW-ADP)

KTE62971-96T 96T
EUR 572
Description: Quantitative sandwich ELISA for measuring Human High Molecular Weight Adiponectin (HMW-ADP) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Chitosan, low molecular weight

GC9009-100G 100 g
EUR 118

Chitosan, low molecular weight

GC9009-50G 50 g
EUR 76

L-Arginine hydrochloride, GlenCell, suitable for cell culture

GM1372-1KG 1 kg
EUR 158

5-20% 12-well PAGEL 10/pk for low molecular weight

2331120 1unit
EUR 377

Stachydrine (hydrochloride)

C3648-100 100 mg
EUR 119
Description: Stachydrine is an anti-metastatic agent.Stachydrine, a pyrrolidine betaine, was first isolated from seed husk and the pulp of the fruit of C. Leonurus, and many other Asian plants and fruits.

Stachydrine (hydrochloride)

C3648-1000 1 g
EUR 467
Description: Stachydrine is an anti-metastatic agent.Stachydrine, a pyrrolidine betaine, was first isolated from seed husk and the pulp of the fruit of C. Leonurus, and many other Asian plants and fruits.

Stachydrine (hydrochloride)

C3648-250 250 mg
EUR 206
Description: Stachydrine is an anti-metastatic agent.Stachydrine, a pyrrolidine betaine, was first isolated from seed husk and the pulp of the fruit of C. Leonurus, and many other Asian plants and fruits.

Stachydrine (hydrochloride)

C3648-500 500 mg
EUR 328
Description: Stachydrine is an anti-metastatic agent.Stachydrine, a pyrrolidine betaine, was first isolated from seed husk and the pulp of the fruit of C. Leonurus, and many other Asian plants and fruits.

Barnidipine (hydrochloride)

C3727-100 100 mg
EUR 203
Description: Barnidipine is a calcium-channel blocker.A calcium channel, an ion channel which displays selective permeability to calcium ions, is sometimes synonymous as voltage-dependent calcium channel, although there are also ligand-gated calcium channels.

Barnidipine (hydrochloride)

C3727-50 50 mg
EUR 155
Description: Barnidipine is a calcium-channel blocker.A calcium channel, an ion channel which displays selective permeability to calcium ions, is sometimes synonymous as voltage-dependent calcium channel, although there are also ligand-gated calcium channels.

MS049 (hydrochloride)

C3776-10 10 mg
EUR 200
Description: IC50: 34 nM for PRMT4; 43 nM for PRMT6 MS049 is a dual PRMT4 and PRMT6 inhibitor.

MS049 (hydrochloride)

C3776-100 100 mg
EUR 1181
Description: IC50: 34 nM for PRMT4; 43 nM for PRMT6 MS049 is a dual PRMT4 and PRMT6 inhibitor.

MS049 (hydrochloride)

C3776-25 25 mg
EUR 382
Description: IC50: 34 nM for PRMT4; 43 nM for PRMT6 MS049 is a dual PRMT4 and PRMT6 inhibitor.

MS049 (hydrochloride)

C3776-5 5 mg
EUR 139
Description: IC50: 34 nM for PRMT4; 43 nM for PRMT6 MS049 is a dual PRMT4 and PRMT6 inhibitor.

MS049 (hydrochloride)

C3776-5.1 10 mM (in 1mL DMSO)
EUR 150
Description: IC50: 34 nM for PRMT4; 43 nM for PRMT6 MS049 is a dual PRMT4 and PRMT6 inhibitor.

MS049 (hydrochloride)

C3776-50 50 mg
EUR 653
Description: IC50: 34 nM for PRMT4; 43 nM for PRMT6 MS049 is a dual PRMT4 and PRMT6 inhibitor.

Guanabenz (hydrochloride)

C3786-100 100 mg
EUR 231
Description: Guanabenz is an orally active ?2-adrenoceptor agonist with hypotensive effects [1]. The ?2 adrenergic receptors belong to a family of G protein-coupled receptor (GPCR), mediate many physiological actions of the endogenous catecholamines adrenaline and noradrenaline.

Guanabenz (hydrochloride)

C3786-50 50 mg
EUR 144
Description: Guanabenz is an orally active ?2-adrenoceptor agonist with hypotensive effects [1]. The ?2 adrenergic receptors belong to a family of G protein-coupled receptor (GPCR), mediate many physiological actions of the endogenous catecholamines adrenaline and noradrenaline.

Ulixertinib (hydrochloride)

C3921-10 10 mg
EUR 406
Description: Ulixertinib, also named as BVD-523, is a novel and reversible inhibitor of ERK1/2. Ulixertinib potently and selectively inhibits the activity of ERK1 and ERK2 kinases in a reversible, ATP-competitive fashion [1].

Ulixertinib (hydrochloride)

C3921-25 25 mg
EUR 661
Description: Ulixertinib, also named as BVD-523, is a novel and reversible inhibitor of ERK1/2. Ulixertinib potently and selectively inhibits the activity of ERK1 and ERK2 kinases in a reversible, ATP-competitive fashion [1].

Ulixertinib (hydrochloride)

C3921-5 5 mg
EUR 250
Description: Ulixertinib, also named as BVD-523, is a novel and reversible inhibitor of ERK1/2. Ulixertinib potently and selectively inhibits the activity of ERK1 and ERK2 kinases in a reversible, ATP-competitive fashion [1].

Chlorcyclizine (hydrochloride)

C3989-100 100 mg
EUR 118
Description: Chlorcyclizine is a phenylpiperazine antagonist for histamine H1 receptor [1]. The histamine has been involved in modulating many physiological functions of the hypothalamus, such as arousal state, feeding, locomotor activity, and drinking.

Chlorcyclizine (hydrochloride)

C3989-1000 1 g
EUR 595
Description: Chlorcyclizine is a phenylpiperazine antagonist for histamine H1 receptor [1]. The histamine has been involved in modulating many physiological functions of the hypothalamus, such as arousal state, feeding, locomotor activity, and drinking.

Chlorcyclizine (hydrochloride)

C3989-250 250 mg
EUR 210
Description: Chlorcyclizine is a phenylpiperazine antagonist for histamine H1 receptor [1]. The histamine has been involved in modulating many physiological functions of the hypothalamus, such as arousal state, feeding, locomotor activity, and drinking.

Chlorcyclizine (hydrochloride)

C3989-500 500 mg
EUR 357
Description: Chlorcyclizine is a phenylpiperazine antagonist for histamine H1 receptor [1]. The histamine has been involved in modulating many physiological functions of the hypothalamus, such as arousal state, feeding, locomotor activity, and drinking.

Lofexidine (hydrochloride)

C3990-1000 1 g
EUR 126
Description: Lofexidine is a ?2-Receptor agonist for opioid detoxification. Lofexidine shows a strong affinity for the ?2A-receptor subtype [1].

Lofexidine (hydrochloride)

C3990-5.1 10 mM (in 1mL H2O)
EUR 113
Description: Lofexidine is a ?2-Receptor agonist for opioid detoxification. Lofexidine shows a strong affinity for the ?2A-receptor subtype [1].

Double immunofluorescence confocal microscopy of human pores and skin revealed that MR predominantly colocalized with calcitonin-gene-related peptide (CGRP)-immunoreactive (IR) nociceptive neurons – much like rat pores and skin – underscoring a pivotal function for MR in the modulation of ache. The majority of GR-immmunoreactivity was localized in peripheral peptidergic CGRP-IR sensory nerve fibers, however in addition on TH-IR sympathetic postganglionic, and NF200-IR myelinated mechanoreceptive nerve fibers, each inside human and rat pores and skin.